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Overcome Infertilty – Birth Defect Causes of Infertility

As we have mentioned in previous articles, infertility is defined as the inability of a couple to conceive after 12 months of unprotected intercourse. It affects more than 5 million couples in the US alone and many times more worldwide. Due to ignorance of treatment, only 10% seek help from a professional specialist. In this article, we will discuss birth defects that cause infertility.

I. Definition

A birth defect is a problem that occurs when a baby develops inside the mother’s body due to injury or gene defects. Some of them can be treated with medical help, some cannot.

II. A birth defect causes infertility

1. Congenital adrenal hyperplasia

Congenital adrenal hyperplasia, as a genetic disease, occurs at birth and can affect both boys and girls. This is due to a lack of an enzyme that is vital for the adrenal gland to produce the hormones cortisol and aldosterone, resulting in higher than normal levels of the testosterone hormone in the body. While a girl is born with a muscular appearance with high levels of the testosterone hormone, it causes abnormal menstruation and causes infertility. The disease can be difficult to diagnose in a boy, but it can interfere with the growth and normal functioning of the reproductive organ, including the testicles and penis, leading to infertility.

2. Congenital anomaly

Abnormalities at birth can interfere with fertility and cause the pregnancy to end.

a) for men

Epididymis, critorchidism, etc.

b) For women

Abnormal cervix, cervical canal, uterine septum, etc

3. Kritorchism

Critorchilism, also known as undescended testicles, usually occurs in premature babies. If not corrected by the age of six, it can lead to permanent infertility due to the absence of sperm in the semen.

4. Cystic fibrosis

It is a genetic disease that is present at birth. Men with cystic fibrosis were born without the vas deferens, where they connect the testis and epididymis to the ejaculatory duct, causing infertility, which prevents sperm from passing through the penis.

5. Epipades

Epipads is a type of abnormal formation of the penis at birth, when the urethra ends with an opening in the upper part of the penis. Men with epipadiae have normal sperm production, but the ejaculated sperm cannot deposit in the cervix, interfering with sexual erection and causing infertility.

6. Chromosomes

Normally, males have an X and a Y chromosome, while females have an X chromosome. Studies show that infertility can be caused by a genetic abnormality, including an abnormality of part of the Y chromosome and the loss of a large part of the Y chromosome, resulting in low sperm count and impaired fertility.

7. Separate the uterus

A separate uterus is a condition where the uterus is divided into a separate side by the septum. Because the uterus is divided, each side has little room for the fetus to grow. It may not interfere with the implantation of fertilized eggs, but the pregnancy may end in premature birth or miscarriage.

8. Feminization of the testes

It is caused by enzyme defects. Men with testicular feminization look like women, but have both X or Y chromosomes and are unable to respond to the male hormone testosterone.

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